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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE ADCC-POTENT ANTIBODY N60-I3 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120 W69A/S115W MUTANT AND M48U1.
DATE LAST MODIFIED
29 Jul 2020
RELEASE
20 Jul 2016
OBSOLETE
CLASSIFICATION
VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.98
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1128/JVI.01068-16
PDBe
5KJR
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P0C0T5 | HIV-1 ENV | HOMO SAPIENS | HUMAN IMMUNODEFICIENCY VIRUS 1 | -- | ||
| P0C0T5 | FAB HEAVY CHAIN OF ADCC-POTENT ANTI-HIV-1 ANTIBODY N60-I3 | HOMO SAPIENS | HOMO SAPIENS | -- | ||
| P0C0T5 | FAB LIGHT CHAIN OF ADCC-POTENT ANTI-HIV-1 ANTIBODY N60-I3 | HOMO SAPIENS | HOMO SAPIENS | -- | ||
| P0C0T5 | -- | -- | SYNTHETIC CONSTRUCT | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402