5KR8

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5KR8_A

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GENERAL

TITLE

(4~{S},6~{S})-4-[2,4-BIS(FLUORANYL)PHENYL]-6-(3,5-DIMETHYL-1,2-OXAZOL- 4-YL)-4-METHYL-5,6-DIHYDRO-1,3-THIAZIN-2-AMINE (COMPOUND 5) BOUND TO BACE1

DATE LAST MODIFIED

5 Oct 2016

RELEASE

7 Sept 2016

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 61 2 2

RESOLUTION RANGE HIGH

2.118

RESOLUTION RANGE LOW

48.9

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.6B01012

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P56817	BACE1, BACE, KIAA1149	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2, ASP 2, BETA-SITE AMYLOID PREC ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402