5KW2

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5KW2_A

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GENERAL

TITLE

THE EXTRA-HELICAL BINDING SITE OF GPR40 AND THE STRUCTURAL BASIS FOR ALLOSTERIC AGONISM AND INCRETIN STIMULATION

DATE LAST MODIFIED

9 May 2018

RELEASE

2 May 2018

OBSOLETE

CLASSIFICATION

FATTY ACID BINDING PROTEIN/HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

2.76

RESOLUTION RANGE LOW

19.81

PUBMED ID

DOI

10.1038/S41467-017-01240-W

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	O14842	FFAR1, GPR40, E, T4TP126	BACULOVIRUS EXPRESSION VECTOR PFASTBAC1-HM	HUMAN	G-PROTEIN COUPLED RECEPTOR 40,G-PROTEIN COUPLED RE ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402