5L2Z

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5L2Z_1

Chain 5L2Z_H

Chain 5L2Z_L

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GENERAL

TITLE

FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 1-[(2R,15R)-2-[(1-AMINO-4- FLUOROISOQUINOLIN-6-YL)AMINO]-4,15,17-TRIMETHYL-3,12-DIOXO-13-OXA-4, 11-DIAZATRICYCLO[14.2.2.1~6,10~]HENICOSA-1(18),6(21),7,9,16,19- HEXAEN-7-YL]CYCLOHEXANE-1-CARBOXYLIC ACID

DATE LAST MODIFIED

12 Oct 2016

RELEASE

28 Sept 2016

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 41 21 2

RESOLUTION RANGE HIGH

1.79

RESOLUTION RANGE LOW

94.04

PUBMED ID

27612545

DOI

10.1016/J.BMCL.2016.08.088

PDBe

5L2Z

LIGANDS

937718 , 2692058 , 628 , 2730972

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P08709	F7	CRICETINAE	HUMAN	PROCONVERTIN,SERUM PROTHROMBIN CONVERSION ACCELERA ...	Mutations
	P08709	F7	CRICETINAE	HUMAN	PROCONVERTIN,SERUM PROTHROMBIN CONVERSION ACCELERA ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402