5L5J

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5L5J_A

Chain 5L5J_B

Chain 5L5J_C

Chain 5L5J_D

Chain 5L5J_E

Chain 5L5J_F

Chain 5L5J_G

Chain 5L5J_H

Chain 5L5J_I

Chain 5L5J_J

Chain 5L5J_K

Chain 5L5J_L

Chain 5L5J_M

Chain 5L5J_N

Chain 5L5J_O

Chain 5L5J_P

Chain 5L5J_Q

Chain 5L5J_R

Chain 5L5J_S

Chain 5L5J_T

Chain 5L5J_U

Chain 5L5J_V

Chain 5L5J_W

Chain 5L5J_X

Chain 5L5J_Y

Chain 5L5J_Z

Chain 5L5J_a

Chain 5L5J_b

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GENERAL

TITLE

YEAST 20S PROTEASOME WITH HUMAN BETA5I (1-138) AND HUMAN BETA6 (97- 111; 118-133) IN COMPLEX WITH EPOXYKETONE INHIBITOR 14

DATE LAST MODIFIED

14 Dec 2016

RELEASE

9 Nov 2016

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.9

RESOLUTION RANGE LOW

PUBMED ID

27789522

DOI

10.15252/EMBJ.201695222

PDBe

5L5J

LIGANDS

2952267 , 2733538 , 10130 , 2694373

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
O18423	PRE8, PRS4, YML092C	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT Y7,MULTICATALYTIC ENDOPEPTIDASE ...
P03051	PRE9, PRS5, YGR135W	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT Y13,MULTICATALYTIC ENDOPEPTIDASE ...
Q6RYW5	PRE6, YOL038W	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT PRE6,MULTICATALYTIC ENDOPEPTIDAS ...
O18423	PUP2, DOA5, YGR253C, G9155	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT PUP2,MULTICATALYTIC ENDOPEPTIDAS ...
Q02767	PRE5, YMR314W, YM9924.06	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT PRE5,MULTICATALYTIC ENDOPEPTIDAS ...
P21242	PRE10, PRC1, PRS1, YOR362C, O6650	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT C1,MULTICATALYTIC ENDOPEPTIDASE ...	Mutations
Q6RYW5	SCL1, PRC2, PRS2, YGL011C	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT C7-ALPHA,MULTICATALYTIC ENDOPEPT ...
P03051	PUP1, YOR157C	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT PUP1,MULTICATALYTIC ENDOPEPTIDAS ...
Q6RYW5	PUP3, YER094C	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT PUP3,MULTICATALYTIC ENDOPEPTIDAS ...
O18423	PRE1, YER012W	SACCHAROMYCES CEREVISIAE S288C	BAKER'S YEAST	MACROPAIN SUBUNIT C11,MULTICATALYTIC ENDOPEPTIDASE ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402