5LGE

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5LGE_1

Bioassembly 5LGE_2

Chain 5LGE_A

Chain 5LGE_B

Chain 5LGE_C

Chain 5LGE_D

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Focus

Transparency

GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN IDH1 MUTANT (R132H) IN COMPLEX WITH NADP+ AND AN INHIBITOR RELATED TO BAY 1436032

DATE LAST MODIFIED

22 Mar 2017

RELEASE

8 Feb 2017

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

2.7

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1007/S00401-017-1677-Y

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
O75164	IDH1, PICD	ESCHERICHIA COLI	HUMAN	IDH,CYTOSOLIC NADP-ISOCITRATE DEHYDROGENASE,IDP,NA ...
O75874	IDH1, PICD	ESCHERICHIA COLI	HUMAN	IDH,CYTOSOLIC NADP-ISOCITRATE DEHYDROGENASE,IDP,NA ...	Mutations
O75874	IDH1, PICD	ESCHERICHIA COLI	HUMAN	IDH,CYTOSOLIC NADP-ISOCITRATE DEHYDROGENASE,IDP,NA ...	Mutations
O75874	IDH1, PICD	ESCHERICHIA COLI	HUMAN	IDH,CYTOSOLIC NADP-ISOCITRATE DEHYDROGENASE,IDP,NA ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402