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GENERAL
TITLE
STRUCTURE OF THE KDM1A/COREST COMPLEX WITH THE INHIBITOR 4-ETHYL-N-[3- (METHOXYMETHYL)-2-[[4-[[(3R)-PYRROLIDIN-3- YL]METHOXY]PHENOXY]METHYL]PHENYL]THIENO[3,2-B]PYRROLE-5-CARBOXAMIDE
DATE LAST MODIFIED
16 Oct 2019
RELEASE
22 Feb 2017
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
3.05
RESOLUTION RANGE LOW
71.38
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.6B01019

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O60341 KDM1A, AOF2, KDM1, KIAA0601, LSD1 ESCHERICHIA COLI HUMAN BRAF35-HDAC COMPLEX PROTEIN BHC110,FLAVIN-CONTAINING AMINEOXIDASE DOMAIN-CONTAINING PROTEIN 2 HUMAN
BRAF35-HDAC COMPLEX PROTEIN BHC110,FLAVIN-CONTAINI ...
Mutations
Q9UKL0 RCOR1, KIAA0071, RCOR ESCHERICHIA COLI HUMAN PROTEIN COREST HUMAN
PROTEIN COREST
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402