5LIK

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5LIK_X

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN AKR1B10 COMPLEXED WITH NADP+ AND THE INHIBITOR MK181

DATE LAST MODIFIED

2 Nov 2016

RELEASE

27 Jul 2016

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 31

RESOLUTION RANGE HIGH

2.05

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACSCHEMBIO.6B00382

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	O60218	AKR1B10, AKR1B11	ESCHERICHIA COLI	HUMAN	ARL-1,ALDOSE REDUCTASE-LIKE,ALDOSE REDUCTASE-RELAT ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402