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GENERAL
TITLE
X-RAY CRYSTAL STRUCTURE OF N-ACETYLNEURAMINIC ACID LYASE IN COMPLEX WITH PYRUVATE, WITH THE PHENYLALANINE AT POSITION 190 REPLACED WITH THE NON-CANONICAL AMINO ACID DIHYDROXYPROPYLCYSTEINE.
DATE LAST MODIFIED
30 Aug 2017
RELEASE
22 Mar 2017
OBSOLETE
CLASSIFICATION
LYASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
75.54
PUBMED ID
DOI
10.1073/PNAS.1616816114

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q2G160 NANA, SAOUHSC_00295 ESCHERICHIA COLI BL21(DE3) STAPHYLOCOCCUS AUREUS (STRAIN NCTC 8325)
NEU5AC LYASE,N-ACETYLNEURAMINATE PYRUVATE-LYASE,N- ...
Mutations
Q2G160 NANA, SAOUHSC_00295 ESCHERICHIA COLI BL21(DE3) STAPHYLOCOCCUS AUREUS (STRAIN NCTC 8325)
NEU5AC LYASE,N-ACETYLNEURAMINATE PYRUVATE-LYASE,N- ...
Mutations
Q2G160 NANA, SAOUHSC_00295 ESCHERICHIA COLI BL21(DE3) STAPHYLOCOCCUS AUREUS (STRAIN NCTC 8325)
NEU5AC LYASE,N-ACETYLNEURAMINATE PYRUVATE-LYASE,N- ...
Mutations
Q2G160 NANA, SAOUHSC_00295 ESCHERICHIA COLI BL21(DE3) STAPHYLOCOCCUS AUREUS (STRAIN NCTC 8325)
NEU5AC LYASE,N-ACETYLNEURAMINATE PYRUVATE-LYASE,N- ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402