5LVX

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5LVX_1

Chain 5LVX_A

Chain 5LVX_B

Chain 5LVX_C

Chain 5LVX_D

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GENERAL

TITLE

CRYSTAL STRUCTURE OF GLUCOCEREBROSIDASE WITH AN INHIBITORY QUINAZOLINE MODULATOR

DATE LAST MODIFIED

29 Jul 2020

RELEASE

25 Oct 2017

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.2

RESOLUTION RANGE LOW

102.65

PUBMED ID

DOI

10.1021/JACS.7B13003

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P04062	GBA, GC, GLUC	HOMO SAPIENS	HUMAN	ACID BETA-GLUCOSIDASE,ALGLUCERASE,BETA-GLUCOCEREBR ...	Mutations
Q8DIS5	GBA, GC, GLUC	HOMO SAPIENS	HUMAN	ACID BETA-GLUCOSIDASE,ALGLUCERASE,BETA-GLUCOCEREBR ...
P04062	GBA, GC, GLUC	HOMO SAPIENS	HUMAN	ACID BETA-GLUCOSIDASE,ALGLUCERASE,BETA-GLUCOCEREBR ...	Mutations
P43405	GBA, GC, GLUC	HOMO SAPIENS	HUMAN	ACID BETA-GLUCOSIDASE,ALGLUCERASE,BETA-GLUCOCEREBR ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402