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GENERAL
TITLE
CRYSTAL STRUCTURE OF AURORA-A BOUND TO A HYDROCARBON-STAPLED PROTEOMIMETIC OF TPX2
DATE LAST MODIFIED
16 Oct 2019
RELEASE
2 Nov 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
2.08
RESOLUTION RANGE LOW
61.98
PUBMED ID
DOI
10.1021/ACSCHEMBIO.6B00727

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O14965 AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6 ESCHERICHIA COLI HUMAN AURORA 2,AURORA/IPL1-RELATED KINASE 1,HARK1,BREAST TUMOR-AMPLIFIED KINASE,SERINE/THREONINE-PROTEIN KINASE 15,SERINE/THREONINE-PROTEIN KINASE 6,SERINE/THREONINE-PROTEIN KINASE AURORA-A HUMAN
AURORA 2,AURORA/IPL1-RELATED KINASE 1,HARK1,BREAST ...
Mutations
Q9ULW0 -- -- HUMAN DIFFERENTIALLY EXPRESSED IN CANCEROUS AND NON-CANCEROUS LUNGCELLS 2,DIL-2,HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 519,HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 90,PROTEIN FLS353,RESTRICTED EXPRESSION PROLIFERATION-ASSOCIATED PROTEIN 100,P100 HUMAN
DIFFERENTIALLY EXPRESSED IN CANCEROUS AND NON-CANC ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402