5LYX

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5LYX_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX; WITH AN INHIBITOR 5-((R)-1-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL- PYRROLIDIN-2-YLMETHOXY)-ISOQUINOLINE

DATE LAST MODIFIED

RELEASE

16 Aug 2017

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 2 2 21

RESOLUTION RANGE HIGH

1.9

RESOLUTION RANGE LOW

PUBMED ID

27998678

DOI

10.1016/J.BMCL.2016.12.019

PDBe

5LYX

LIGANDS

2982198 , 2694450

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P50579	METAP2, MNPEP, P67EIF2	SPODOPTERA FRUGIPERDA	HUMAN	METAP 2,INITIATION FACTOR 2-ASSOCIATED 67 KDA GLYC ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402