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GENERAL
TITLE
SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW TRIAZOLO AND IMIDAZOLOPYRIDINE RORGT INVERSE AGONISTS
DATE LAST MODIFIED
19 Dec 2018
RELEASE
14 Dec 2016
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61
RESOLUTION RANGE HIGH
1.77
RESOLUTION RANGE LOW
19.87
PUBMED ID
DOI
10.1002/CMDC.201600500
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P51449 RORC, NR1F3, RORG, RZRG ESCHERICHIA COLI BL21 HUMAN NUCLEAR RECEPTOR RZR-GAMMA,NUCLEAR RECEPTOR SUBFAMILY 1GROUP F MEMBER 3,RAR-RELATED ORPHAN RECEPTOR C,RETINOID-RELATEDORPHAN RECEPTOR-GAMMA HUMAN
NUCLEAR RECEPTOR RZR-GAMMA,NUCLEAR RECEPTOR SUBFAM ...
Mutations
P51449 RORC, NR1F3, RORG, RZRG ESCHERICHIA COLI BL21 HUMAN NUCLEAR RECEPTOR RZR-GAMMA,NUCLEAR RECEPTOR SUBFAMILY 1GROUP F MEMBER 3,RAR-RELATED ORPHAN RECEPTOR C,RETINOID-RELATEDORPHAN RECEPTOR-GAMMA HUMAN
NUCLEAR RECEPTOR RZR-GAMMA,NUCLEAR RECEPTOR SUBFAM ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402