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GENERAL
TITLE
CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH ACTIVE SITE INHIBITOR GRL- 8234 AND EXOSITE PEPTIDE
DATE LAST MODIFIED
1 Nov 2017
RELEASE
27 Sept 2017
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
2.49
RESOLUTION RANGE LOW
48.8
PUBMED ID
DOI
10.1016/J.EBIOM.2017.09.004
PDBe
5MCO
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P56817 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ... | Mutations | |
| -- | -- | HUMAN | -- | HUMAN | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402