5MCO

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5MCO_A

Chain 5MCO_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH ACTIVE SITE INHIBITOR GRL- 8234 AND EXOSITE PEPTIDE

DATE LAST MODIFIED

1 Nov 2017

RELEASE

27 Sept 2017

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 32 2 1

RESOLUTION RANGE HIGH

2.49

RESOLUTION RANGE LOW

48.8

PUBMED ID

DOI

10.1016/J.EBIOM.2017.09.004

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P56817	BACE1, BACE, KIAA1149	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ...	Mutations
		--	--	HUMAN	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402