5MCQ logo

5MCQ

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH ACTIVE SITE AND EXOSITE BINDING PEPTIDE INHIBITOR
DATE LAST MODIFIED
1 Nov 2017
RELEASE
27 Sept 2017
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
1.82
RESOLUTION RANGE LOW
48.58
PUBMED ID
DOI
10.1016/J.EBIOM.2017.09.004

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 HUMAN
ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ...
Mutations
-- -- HOMO SAPIENS -- HOMO SAPIENS --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402