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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE GLUK1 LIGAND-BINDING DOMAIN IN COMPLEX WITH KAINATE AND BPAM-521 AT 2.18 A RESOLUTION
DATE LAST MODIFIED
17 Jan 2018
RELEASE
12 Apr 2017
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
2.18
RESOLUTION RANGE LOW
47.61
PUBMED ID
DOI
10.1124/MOL.116.107599
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P22756 GRIK1, GLUR5 ESCHERICHIA COLI RAT GLUK1,GLUTAMATE RECEPTOR 5,GLUR5,GLUK1,GLUTAMATE RECEPTOR 5,GLUR5BINDING DOMAIN OF GLUK1. TRANSMEMBRANE REGIONS WERE GENETICALLYREMOVED AND REPLACED WITH A GLY-THR LINKER (RESIDUES 545 AND 546 OFTHE STRUCTURE). THEREFORE, THE SEQUENCE MATCHES DISCONTINUOUSLY WITHTHE REFERENCE DATABASE (430-544, 667-805). RESIDUE 429 IS A REMNANTFROM CLONING. RAT
GLUK1,GLUTAMATE RECEPTOR 5,GLUR5,GLUK1,GLUTAMATE R ...
Mutations
P22756 GRIK1, GLUR5 ESCHERICHIA COLI RAT GLUK1,GLUTAMATE RECEPTOR 5,GLUR5,GLUK1,GLUTAMATE RECEPTOR 5,GLUR5BINDING DOMAIN OF GLUK1. TRANSMEMBRANE REGIONS WERE GENETICALLYREMOVED AND REPLACED WITH A GLY-THR LINKER (RESIDUES 545 AND 546 OFTHE STRUCTURE). THEREFORE, THE SEQUENCE MATCHES DISCONTINUOUSLY WITHTHE REFERENCE DATABASE (430-544, 667-805). RESIDUE 429 IS A REMNANTFROM CLONING. RAT
GLUK1,GLUTAMATE RECEPTOR 5,GLUR5,GLUK1,GLUTAMATE R ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402