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GENERAL
TITLE
A MODULAR ROUTE TO NOVEL POTENT AND SELECTIVE INHIBITORS OF RHOMBOID INTRAMEMBRANE PROTEASES
DATE LAST MODIFIED
29 Jul 2020
RELEASE
15 Nov 2017
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
H 3 2
RESOLUTION RANGE HIGH
1.787
RESOLUTION RANGE LOW
44.97
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2017.09.007

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
B7MDQ0 GLPG, ECS88_3813 ESCHERICHIA COLI BL21(DE3) ESCHERICHIA COLI O45:K1 (STRAIN S88 / EXPEC) INTRAMEMBRANE SERINE PROTEASE ESCHERICHIA COLI O45:K1 (STRAIN S88 / EXPEC)
INTRAMEMBRANE SERINE PROTEASE
Mutations
-- -- SYNTHETIC CONSTRUCT -- SYNTHETIC CONSTRUCT --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402