5MTF

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5MTF_1

Chain 5MTF_A

Chain 5MTF_C

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GENERAL

TITLE

A MODULAR ROUTE TO NOVEL POTENT AND SELECTIVE INHIBITORS OF RHOMBOID INTRAMEMBRANE PROTEASES

DATE LAST MODIFIED

29 Jul 2020

RELEASE

15 Nov 2017

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

H 3 2

RESOLUTION RANGE HIGH

1.787

RESOLUTION RANGE LOW

44.97

PUBMED ID

DOI

10.1016/J.CHEMBIOL.2017.09.007

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	B7MDQ0	GLPG, ECS88_3813	ESCHERICHIA COLI BL21(DE3)	ESCHERICHIA COLI O45:K1 (STRAIN S88 / EXPEC)	INTRAMEMBRANE SERINE PROTEASE	Mutations
		--	--	SYNTHETIC CONSTRUCT	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402