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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN CASPASE-1 WITH (3S,6S,10AS)-N-((2S,3S)-2- HYDROXY-5-OXOTETRAHYDROFURAN-3-YL)-6-(ISOQUINOLINE-1-CARBOXAMIDO)-5- OXODECAHYDROPYRROLO[1,2-A]AZOCINE-3-CARBOXAMIDE (PGE-3935199)
DATE LAST MODIFIED
-
RELEASE
28 Feb 2018
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 21 2
RESOLUTION RANGE HIGH
2.53
RESOLUTION RANGE LOW
50.39
PUBMED ID
-
DOI
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P29466 CASP1, IL1BC, IL1BCE ESCHERICHIA COLI HUMAN CASP-1,INTERLEUKIN-1 BETA CONVERTASE,IL-1BC,INTERLEUKIN-1BETA-CONVERTING ENZYME,IL-1 BETA-CONVERTING ENZYME,P45 HUMAN
CASP-1,INTERLEUKIN-1 BETA CONVERTASE,IL-1BC,INTERL ...
Mutations
P29466 CASP1, IL1BC, IL1BCE ESCHERICHIA COLI HUMAN CASP-1,INTERLEUKIN-1 BETA CONVERTASE,IL-1BC,INTERLEUKIN-1BETA-CONVERTING ENZYME,IL-1 BETA-CONVERTING ENZYME,P45 HUMAN
CASP-1,INTERLEUKIN-1 BETA CONVERTASE,IL-1BC,INTERL ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402