5MU8

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5MU8_1

Bioassembly 5MU8_2

Bioassembly 5MU8_3

Bioassembly 5MU8_4

Bioassembly 5MU8_5

Bioassembly 5MU8_6

Bioassembly 5MU8_7

Bioassembly 5MU8_8

Bioassembly 5MU8_9

Chain 5MU8_A

Chain 5MU8_B

Chain 5MU8_C

Chain 5MU8_D

Chain 5MU8_F

Chain 5MU8_G

Chain 5MU8_H

Chain 5MU8_I

Chain 5MU8_J

Chain 5MU8_K

Chain 5MU8_L

Chain 5MU8_M

Chain 5MU8_N

Chain 5MU8_O

Chain 5MU8_P

Chain 5MU8_Q

Chain 5MU8_R

Chain 5MU8_S

Chain 5MU8_T

Chain 5MU8_U

Chain 5MU8_V

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GENERAL

TITLE

HUMAN TNF-ALPHA IN COMPLEX WITH JNJ525

DATE LAST MODIFIED

20 Feb 2019

RELEASE

29 Mar 2017

OBSOLETE

CLASSIFICATION

CYTOKINE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

RESOLUTION RANGE LOW

184.24

PUBMED ID

28300404

DOI

10.1021/ACS.JMEDCHEM.6B01836

PDBe

5MU8

LIGANDS

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q5ZKX9	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
Q96LB9	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...
P0DTC2	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P0DTC2	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...
P0DTC2	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P04818	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402