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GENERAL
TITLE
STRUCTURE OF GLUK1 LIGAND-BINDING DOMAIN (S1S2) IN COMPLEX WITH LM-12B AT 2.05 A RESOLUTION
DATE LAST MODIFIED
7 Mar 2018
RELEASE
26 Jul 2017
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.05
RESOLUTION RANGE LOW
87.216
PUBMED ID
DOI
10.1021/ACSCHEMNEURO.7B00201
PDBe
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Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P22756 | GRIK1, GLUR5 | ESCHERICHIA COLI BL21(DE3) | RAT | GLUK1,GLUTAMATE RECEPTOR 5,GLUR5THE PROTEIN CRYSTALLIZED IS THE EXTRACELLULAR LIGAND-BINDING DOMAINOF GLUK1. TRANSMEMBRANE REGIONS WERE REPLACED WITH A GLY-THR LINKER(RESIDUES 117-118). THE SEQUENCE MATCHES DISCONTINOUSLY WITHREFERENCE DATABASE (430-544, 667-805). THERE IS A SEQUENCE CONFLICTAT RESIDUE 34 (462) OF THE CRYSTALLIZED PROTEIN DUE TO DIFFERENCES INDATABASE SEQUENCE (SEE GENBANK ACCESION NO.AAA02874). GLY1 IS ACLONING REMNANT. | RAT | GLUK1,GLUTAMATE RECEPTOR 5,GLUR5THE PROTEIN CRYSTA ... | Mutations | |
| P22756 | GRIK1, GLUR5 | ESCHERICHIA COLI BL21(DE3) | RAT | GLUK1,GLUTAMATE RECEPTOR 5,GLUR5THE PROTEIN CRYSTALLIZED IS THE EXTRACELLULAR LIGAND-BINDING DOMAINOF GLUK1. TRANSMEMBRANE REGIONS WERE REPLACED WITH A GLY-THR LINKER(RESIDUES 117-118). THE SEQUENCE MATCHES DISCONTINOUSLY WITHREFERENCE DATABASE (430-544, 667-805). THERE IS A SEQUENCE CONFLICTAT RESIDUE 34 (462) OF THE CRYSTALLIZED PROTEIN DUE TO DIFFERENCES INDATABASE SEQUENCE (SEE GENBANK ACCESION NO.AAA02874). GLY1 IS ACLONING REMNANT. | RAT | GLUK1,GLUTAMATE RECEPTOR 5,GLUR5THE PROTEIN CRYSTA ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402