5NW0

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5NW0_1

Bioassembly 5NW0_2

Bioassembly 5NW0_3

Bioassembly 5NW0_4

Chain 5NW0_A

Chain 5NW0_B

Chain 5NW0_C

Chain 5NW0_D

Chain 5NW0_E

Chain 5NW0_F

Chain 5NW0_G

Chain 5NW0_H

Chain 5NW0_I

Chain 5NW0_J

Chain 5NW0_K

Chain 5NW0_L

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GENERAL

TITLE

PVHL:ELOB:ELOC IN COMPLEX WITH (2S,4R)-1-((S)-2-(1- ACETAMIDOCYCLOPROPANECARBOXAMIDO)-3,3-DIMETHYLBUTANOYL)-4-HYDROXY-N- (4-(4-METHYLTHIAZOL-5-YL)BENZYL)PYRROLIDINE-2-CARBOXAMIDE (LIGAND 17)

DATE LAST MODIFIED

7 Feb 2018

RELEASE

20 Sept 2017

OBSOLETE

CLASSIFICATION

LIGASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 41 2 2

RESOLUTION RANGE HIGH

2.3

RESOLUTION RANGE LOW

49.57

PUBMED ID

28853884

DOI

10.1021/ACS.JMEDCHEM.7B00675

PDBe

5NW0

LIGANDS

809851 , 2692073

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q9LS03	ELOB, TCEB2	ESCHERICHIA COLI	HUMAN	ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
P54517	ELOC, TCEB1	ESCHERICHIA COLI	HUMAN	ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
P54517	VHL	ESCHERICHIA COLI	HUMAN	PROTEIN G7,PVHL
P63316	ELOB, TCEB2	ESCHERICHIA COLI	HUMAN	ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
P54517	ELOC, TCEB1	ESCHERICHIA COLI	HUMAN	ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
P54517	VHL	ESCHERICHIA COLI	HUMAN	PROTEIN G7,PVHL
Q15370	ELOB, TCEB2	ESCHERICHIA COLI	HUMAN	ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...	Mutations
P54517	ELOC, TCEB1	ESCHERICHIA COLI	HUMAN	ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
P54517	VHL	ESCHERICHIA COLI	HUMAN	PROTEIN G7,PVHL
P30405	ELOB, TCEB2	ESCHERICHIA COLI	HUMAN	ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402