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GENERAL
TITLE
DISCOVERY OF SMALL MOLECULES BINDING TO KRAS VIA HIGH AFFINITY ANTIBODY FRAGMENT COMPETITION METHOD.
DATE LAST MODIFIED
16 Oct 2019
RELEASE
22 Aug 2018
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.07
RESOLUTION RANGE LOW
41.72
PUBMED ID
DOI
10.1038/S41467-018-05707-2

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402