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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE ACVR1 (ALK2) KINASE IN COMPLEX WITH CYCLICAL INHIBITOR OD36.
DATE LAST MODIFIED
13 Dec 2017
RELEASE
27 Sept 2017
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.56
RESOLUTION RANGE LOW
75.39
PUBMED ID
-
DOI
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q04771 ACVR1, ACVRLK2 SPODOPTERA FRUGIPERDA HUMAN ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LIKE KINASE2,ALK-2,SERINE/THREONINE-PROTEIN KINASE RECEPTOR R1,SKR1,TGF-BSUPERFAMILY RECEPTOR TYPE I,TSR-IQ04771 HUMAN
ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...
Mutations
Q04771 ACVR1, ACVRLK2 SPODOPTERA FRUGIPERDA HUMAN ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LIKE KINASE2,ALK-2,SERINE/THREONINE-PROTEIN KINASE RECEPTOR R1,SKR1,TGF-BSUPERFAMILY RECEPTOR TYPE I,TSR-IQ04771 HUMAN
ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...
Mutations
Q04771 ACVR1, ACVRLK2 SPODOPTERA FRUGIPERDA HUMAN ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LIKE KINASE2,ALK-2,SERINE/THREONINE-PROTEIN KINASE RECEPTOR R1,SKR1,TGF-BSUPERFAMILY RECEPTOR TYPE I,TSR-IQ04771 HUMAN
ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...
Mutations
Q04771 ACVR1, ACVRLK2 SPODOPTERA FRUGIPERDA HUMAN ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LIKE KINASE2,ALK-2,SERINE/THREONINE-PROTEIN KINASE RECEPTOR R1,SKR1,TGF-BSUPERFAMILY RECEPTOR TYPE I,TSR-IQ04771 HUMAN
ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402