5QD3 logo

5QD3

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF BACE COMPLEX WITH BMC010
DATE LAST MODIFIED
10 Feb 2021
RELEASE
3 Jun 2020
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.46
RESOLUTION RANGE LOW
71.35
PUBMED ID
DOI
10.1007/S10822-020-00289-Y
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 HUMAN
ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ...
Mutations
P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 HUMAN
ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ...
Mutations
P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 HUMAN
ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402