3D Structure View
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GENERAL
TITLE
CRYSTAL STRUCTURE OF BACE COMPLEX WITH BMC004
DATE LAST MODIFIED
10 Feb 2021
RELEASE
3 Jun 2020
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.505
RESOLUTION RANGE LOW
27.603
PUBMED ID
DOI
10.1007/S10822-020-00289-Y
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P56817 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ... | Mutations | |
| P56817 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ... | Mutations | |
| P56817 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402