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GENERAL
TITLE
CRYSTAL STRUCTURE OF MURINE 11B- HYDROXYSTEROIDDEHYDROGENASE COMPLEXED WITH 2-(3-(1-(4- CHLOROPHENYL)CYCLOPROPYL)-[1,2,4]TRIAZOLO[4,3- A]PYRIDIN-8- YL)PROPAN-2-OL
DATE LAST MODIFIED
12 May 2021
RELEASE
19 Dec 2018
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 2 2
RESOLUTION RANGE HIGH
2.65
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.8B00307
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P50172 HSD11B1, HSD11 ESCHERICHIA COLI BL21(DE3) MOUSE
11-BETA-HYDROXYSTEROID DEHYDROGENASE 1,11-BETA-HSD ...
Mutations
P50172 HSD11B1, HSD11 ESCHERICHIA COLI BL21(DE3) MOUSE
11-BETA-HYDROXYSTEROID DEHYDROGENASE 1,11-BETA-HSD ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402