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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS GENOTYPE 2A STRAIN JFH1 NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 6- [ETHYL(METHYLSULFONYL)AMINO]-2-(4-FLUOROPHENYL)-N-METHYL-5-(3-{[1- (PYRIMIDIN-2-YL)CYCLOPROPYL]CARBAMOYL}PHENYL)-1-BENZOFURAN-3- CARBOXAMIDE
DATE LAST MODIFIED
12 May 2021
RELEASE
21 Nov 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.08
RESOLUTION RANGE LOW
62.04
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.8B00379

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q99IB8 -- ESCHERICHIA COLI BL21(DE3) HEPACIVIRUS C -- HEPACIVIRUS C -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402