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GENERAL
TITLE
FACTOR XIA IN COMPLEX WITH THE INHIBITOR METHYL [(3R,7S)-7-{[5-AMINO- 1-(3-CHLORO-2-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBONYL]AMINO}-3-METHYL-2- OXO-2,3,4,5,6,7-HEXAHYDRO-1H-12,8-(METHENO)-1,9- BENZODIAZACYCLOTETRADECIN-15-YL]CARBAMATE
DATE LAST MODIFIED
12 May 2021
RELEASE
25 Dec 2019
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
2.23
RESOLUTION RANGE LOW
68.45
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B01768
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P03951 F11 ESCHERICHIA COLI HUMAN FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA HUMAN
FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402