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GENERAL
TITLE
FACTOR XIA IN COMPLEX WITH THE INHIBITOR METHYL [(3R,7S)-7-{[1-(3- CHLORO-2-FLUOROPHENYL)-5-METHYL-1H-IMIDAZOLE-4-CARBONYL]AMINO}-3- METHYL-2-OXO-2,3,4,5,6,7-HEXAHYDRO-1H-12,8-(METHENO)-1,9- BENZODIAZACYCLOTETRADECIN-15-YL]CARBAMATE
DATE LAST MODIFIED
12 May 2021
RELEASE
25 Dec 2019
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
2.53
RESOLUTION RANGE LOW
105.66
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B01768
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P03951 F11 ESCHERICHIA COLI BL21(DE3) HUMAN FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA HUMAN
FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA
Mutations
P03951 F11 ESCHERICHIA COLI BL21(DE3) HUMAN FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA HUMAN
FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402