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GENERAL
TITLE
FACTOR XIA IN COMPLEX WITH THE INHIBITOR METHYL [(2R,7S)-7-({(2E)-3- [5-CHLORO-2-(1H-TETRAZOL-1-YL)PHENYL]PROP-2-ENOYL}AMINO)-2- (TRIFLUOROMETHYL)-2,3,4,5,6,7-HEXAHYDRO-1H-8,11-EPIMINO-1,9- BENZODIAZACYCLOTRIDECIN-14-YL]CARBAMATE
DATE LAST MODIFIED
12 May 2021
RELEASE
29 Jan 2020
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2020.126949
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P03951 F11 ESCHERICHIA COLI BL21(DE3) HUMAN FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA HUMAN
FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402