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GENERAL
TITLE
TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH 6-[1- (2,2-DIFLUOROETHYL)-4-(6-METHYLPYRIDIN-2-YL)-1H-IMIDAZOL-5- YL]IMIDAZO[1,2-A]PYRIDINE
DATE LAST MODIFIED
17 Nov 2021
RELEASE
5 Feb 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.83
RESOLUTION RANGE LOW
45.17
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.9B00552
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P36897 TGFBR1, ALK5, SKR4 SPODOPTERA FRUGIPERDA HUMAN TGFR-1,ACTIVIN A RECEPTOR TYPE II-LIKE PROTEIN KINASE OF53KD,ACTIVIN RECEPTOR-LIKE KINASE 5,ALK5,SERINE/THREONINE-PROTEINKINASE RECEPTOR R4,SKR4,TGF-BETA TYPE I RECEPTOR,TRANSFORMING GROWTHFACTOR-BETA RECEPTOR TYPE I,TBETAR-I HUMAN
TGFR-1,ACTIVIN A RECEPTOR TYPE II-LIKE PROTEIN KIN ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402