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GENERAL
TITLE
STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
DATE LAST MODIFIED
30 Nov 2016
RELEASE
19 Oct 2016
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
8
RESOLUTION RANGE LOW
8
PUBMED ID
DOI
10.1073/PNAS.1614614113
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P35998 -- -- HUMAN 26S PROTEASOME AAA-ATPASE SUBUNIT RPT1,PROTEASOME 26SSUBUNIT ATPASE 2,PROTEIN MSS1 HUMAN
26S PROTEASOME AAA-ATPASE SUBUNIT RPT1,PROTEASOME ...
Mutations
P62191 -- -- HUMAN P26S4,26S PROTEASOME AAA-ATPASE SUBUNIT RPT2,PROTEASOME 26SSUBUNIT ATPASE 1 HUMAN
P26S4,26S PROTEASOME AAA-ATPASE SUBUNIT RPT2,PROTE ...
Mutations
P62195 -- -- HUMAN 26S PROTEASOME AAA-ATPASE SUBUNIT RPT6,PROTEASOME 26SSUBUNIT ATPASE 5,PROTEASOME SUBUNIT P45,THYROID HORMONE RECEPTOR-INTERACTING PROTEIN 1,TRIP1,P45/SUG HUMAN
26S PROTEASOME AAA-ATPASE SUBUNIT RPT6,PROTEASOME ...
Mutations
P43686 -- -- HUMAN 26S PROTEASOME AAA-ATPASE SUBUNIT RPT3,MB67-INTERACTINGPROTEIN,MIP224,PROTEASOME 26S SUBUNIT ATPASE 4,TAT-BINDING PROTEIN 7,TBP-7 HUMAN
26S PROTEASOME AAA-ATPASE SUBUNIT RPT3,MB67-INTERA ...
Mutations
P62333 -- -- HUMAN -- HUMAN -- Mutations
P17980 -- -- HUMAN 26S PROTEASOME AAA-ATPASE SUBUNIT RPT5,PROTEASOME 26SSUBUNIT ATPASE 3,PROTEASOME SUBUNIT P50,TAT-BINDING PROTEIN 1,TBP-1 HUMAN
26S PROTEASOME AAA-ATPASE SUBUNIT RPT5,PROTEASOME ...
Mutations
P60900 -- -- HUMAN 27 KDA PROSOMAL PROTEIN,P27K,MACROPAIN IOTA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX IOTA CHAIN,PROTEASOME IOTACHAIN HUMAN
27 KDA PROSOMAL PROTEIN,P27K,MACROPAIN IOTA CHAIN, ...
Mutations
P25787 -- -- HUMAN MACROPAIN SUBUNIT C3,MULTICATALYTIC ENDOPEPTIDASE COMPLEXSUBUNIT C3,PROTEASOME COMPONENT C3 HUMAN
MACROPAIN SUBUNIT C3,MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
P25789 -- -- HUMAN MACROPAIN SUBUNIT C9,MULTICATALYTIC ENDOPEPTIDASE COMPLEXSUBUNIT C9,PROTEASOME COMPONENT C9,PROTEASOME SUBUNIT L HUMAN
MACROPAIN SUBUNIT C9,MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
O14818 -- -- HUMAN PROTEASOME SUBUNIT RC6-1,PROTEASOME SUBUNIT XAPC7 HUMAN
PROTEASOME SUBUNIT RC6-1,PROTEASOME SUBUNIT XAPC7
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402