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GENERAL
TITLE
STRUCTURE OF AN AFFINITY MATURED LAMBDA-IFN/IFN-LAMBDAR1/IL-10RBETA RECEPTOR COMPLEX
DATE LAST MODIFIED
24 Mar 2021
RELEASE
29 Mar 2017
OBSOLETE
CLASSIFICATION
CYTOKINE/CYTOKINE RECEPTOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
2.847
RESOLUTION RANGE LOW
46.241
PUBMED ID
DOI
10.1016/J.IMMUNI.2017.02.017
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q08334 IL10RB, CRFB4, D21S58, D21S66 TRICHOPLUSIA NI HUMAN IL-10RB,CYTOKINE RECEPTOR CLASS-II MEMBER 4,CYTOKINERECEPTOR FAMILY 2 MEMBER 4,CRF2-4,INTERLEUKIN-10 RECEPTOR SUBUNIT 2,IL-10R2 HUMAN
IL-10RB,CYTOKINE RECEPTOR CLASS-II MEMBER 4,CYTOKI ...
Mutations
Q8IU57 IFNLR1, IL28RA, LICR2 HOMO SAPIENS HUMAN IFN-LAMBDA-R1,CYTOKINE RECEPTOR CLASS-II MEMBER 12,CYTOKINERECEPTOR FAMILY 2 MEMBER 12,CRF2-12,INTERLEUKIN-28 RECEPTOR SUBUNITALPHA,IL-28RA,LIKELY INTERLEUKIN OR CYTOKINE RECEPTOR 2,LICR2 HUMAN
IFN-LAMBDA-R1,CYTOKINE RECEPTOR CLASS-II MEMBER 12 ...
Mutations
Q8IZI9 IFNL3, IL28B, IL28C, ZCYTO22 TRICHOPLUSIA NI HUMAN IFN-LAMBDA-3,CYTOKINE ZCYTO22,INTERLEUKIN-28B,IL-28B,INTERLEUKIN-28C,IL-28C HUMAN
IFN-LAMBDA-3,CYTOKINE ZCYTO22,INTERLEUKIN-28B,IL-2 ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402