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GENERAL
TITLE
P110DELTA/P85ALPHA WITH TASELISIB (GDC-0032)
DATE LAST MODIFIED
8 Feb 2017
RELEASE
11 Jan 2017
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.91
RESOLUTION RANGE LOW
86.37
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.6B01363
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O00329 PIK3CD SPODOPTERA FRUGIPERDA HUMAN PTDINS-3-KINASE SUBUNIT DELTA,PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE 110 KDA CATALYTIC SUBUNIT DELTA,P110DELTA HUMAN
PTDINS-3-KINASE SUBUNIT DELTA,PHOSPHATIDYLINOSITOL ...
Mutations
P23727 PIK3R1 SPODOPTERA FRUGIPERDA BOVINE PTDINS-3-KINASE REGULATORY SUBUNIT ALPHA,PHOSPHATIDYLINOSITOL 3-KINASE 85 KDA REGULATORY SUBUNIT ALPHA,PTDINS-3-KINASE REGULATORY SUBUNIT P85-ALPHA BOVINE
PTDINS-3-KINASE REGULATORY SUBUNIT ALPHA,PHOSPHATI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402