5UL1

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5UL1_1

Chain 5UL1_A

Chain 5UL1_B

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GENERAL

TITLE

THE CO-STRUCTURE OF 3-AMINO-6-(4-((1-(DIMETHYLAMINO)PROPAN-2-YL) SULFONYL)PHENYL)-N-PHENYLPYRAZINE-2-CARBOXAMIDE AND A RATIONALLY DESIGNED PI3K-ALPHA MUTANT THAT MIMICS ATR

DATE LAST MODIFIED

14 Jun 2017

RELEASE

10 May 2017

OBSOLETE

CLASSIFICATION

TRANSFERASE/SIGNALING PROTEIN/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.95

RESOLUTION RANGE LOW

47.13

PUBMED ID

28433539

DOI

10.1016/J.JMB.2017.04.006

PDBe

5UL1

LIGANDS

2870577

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q8A712	PIK3CA	UNIDENTIFIED BACULOVIRUS	HUMAN	PTDINS-3-KINASE SUBUNIT ALPHA,PHOSPHATIDYLINOSITOL ...
	P28366	PIK3R1, GRB1	UNIDENTIFIED BACULOVIRUS	HUMAN	PTDINS-3-KINASE REGULATORY SUBUNIT ALPHA,PHOSPHATI ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402