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TITLE
CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH A 12-MER LYSINE- CYSTEINE SIDE CHAIN DITHIOCARBAMATE STAPLED PEPTIDE INHIBITOR PMI
EXPRESSION SYSTEM(S)
EXPERIMENT TYPE
X-RAY DIFFRACTION
ORGANISM(S)
SYNTHETIC CONSTRUCT , HOMO SAPIENS ,
CLASSIFICATION
LIGASE/LIGASE INHIBITOR
SPACE GROUP:
C 2 2 21
RESOLUTION RANGE HIGH:
1.8
RESOLUTION RANGE LOW:
50
DOI:
10.1039/C8SC03275K
EM DATA RESOURCE:
--
DATE DEPOSITED:
2017-04-20 00:00:00
DATE RELEASED:
2018-04-25 00:00:00
DATE REVISED:
2019-12-11 00:00:00
BIOLOGICAL ASSEMBLY:
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3D Structure - 5VK0

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5VK0_Q
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonyms
5VK0_D -- -- SYNTHETIC CONSTRUCT --
5VK0_L -- -- SYNTHETIC CONSTRUCT --
5VK0_J -- -- SYNTHETIC CONSTRUCT --
5VK0_C Q00987 -- -- HUMAN DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,RING-TYPE E3UBIQUITIN TRANSFERASE MDM2,P53-BINDING PROTEIN MDM2
5VK0_X -- -- SYNTHETIC CONSTRUCT --
5VK0_O Q00987 -- -- HUMAN DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,RING-TYPE E3UBIQUITIN TRANSFERASE MDM2,P53-BINDING PROTEIN MDM2
5VK0_U Q00987 -- -- HUMAN DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,RING-TYPE E3UBIQUITIN TRANSFERASE MDM2,P53-BINDING PROTEIN MDM2
5VK0_V -- -- SYNTHETIC CONSTRUCT --
5VK0_F -- -- SYNTHETIC CONSTRUCT --
5VK0_M Q00987 -- -- HUMAN DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,RING-TYPE E3UBIQUITIN TRANSFERASE MDM2,P53-BINDING PROTEIN MDM2