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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN MDM4 IN COMPLEX WITH A 12-MER LYSINE- CYSTEINE SIDE CHAIN DITHIOCARBAMATE STAPLED PEPTIDE INHIBITOR PMI
DATE LAST MODIFIED
13 Mar 2019
RELEASE
25 Apr 2018
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.69
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1039/C8SC03275K
PDBe
5VK1
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| O15151 | -- | -- | HUMAN | DOUBLE MINUTE 4 PROTEIN,MDM2-LIKE P53-BINDING PROT ... | Mutations | |
| P0A334 | -- | -- | SYNTHETIC CONSTRUCT | -- | ||
| O15151 | -- | -- | HUMAN | DOUBLE MINUTE 4 PROTEIN,MDM2-LIKE P53-BINDING PROT ... | Mutations | |
| Q5SJ80 | -- | -- | SYNTHETIC CONSTRUCT | -- | ||
| P04789 | -- | -- | HUMAN | DOUBLE MINUTE 4 PROTEIN,MDM2-LIKE P53-BINDING PROT ... | ||
| -- | -- | SYNTHETIC CONSTRUCT | -- | |||
| O15151 | -- | -- | HUMAN | DOUBLE MINUTE 4 PROTEIN,MDM2-LIKE P53-BINDING PROT ... | Mutations | |
| -- | -- | SYNTHETIC CONSTRUCT | -- | |||
| O15151 | -- | -- | HUMAN | DOUBLE MINUTE 4 PROTEIN,MDM2-LIKE P53-BINDING PROT ... | Mutations | |
| Q15102 | -- | -- | SYNTHETIC CONSTRUCT | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402