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GENERAL
TITLE
DIRECT OBSERVATION OF CONFORMATIONAL POPULATION SHIFTS IN HEMOGLOBIN: CRYSTAL STRUCTURE OF HALF-LIGANDED HEMOGLOBIN AFTER ADDING 4 MM BEZAFIBRATE PH 7.2.
DATE LAST MODIFIED
20 Dec 2017
RELEASE
20 Sept 2017
OBSOLETE
CLASSIFICATION
TRANSPORT PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.64
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1074/JBC.M117.781146
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P69905 -- -- HUMAN
ALPHA-GLOBIN,HEMOGLOBIN ALPHA CHAIN
Mutations
P68871 -- -- HUMAN
BETA-GLOBIN,HEMOGLOBIN BETA CHAIN
Mutations
P69905 -- -- HUMAN
ALPHA-GLOBIN,HEMOGLOBIN ALPHA CHAIN
Mutations
P68871 -- -- HUMAN
BETA-GLOBIN,HEMOGLOBIN BETA CHAIN
Mutations
P69905 -- -- HUMAN
ALPHA-GLOBIN,HEMOGLOBIN ALPHA CHAIN
Mutations
P68871 -- -- HUMAN
BETA-GLOBIN,HEMOGLOBIN BETA CHAIN
Mutations
P69905 -- -- HUMAN
ALPHA-GLOBIN,HEMOGLOBIN ALPHA CHAIN
Mutations
P68871 -- -- HUMAN
BETA-GLOBIN,HEMOGLOBIN BETA CHAIN
Mutations
P69905 -- -- HUMAN
ALPHA-GLOBIN,HEMOGLOBIN ALPHA CHAIN
Mutations
P68871 -- -- HUMAN
BETA-GLOBIN,HEMOGLOBIN BETA CHAIN
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402