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GENERAL
TITLE
CRYSTAL STRUCTURE OF HSP90-ALPHA N-TERMINAL DOMAIN IN COMPLEX WITH 4- (3-ISOPROPYL-4-(4-(1-METHYL-1H-PYRAZOL-4-YL)-1H-IMIDAZOL-1-YL)-1H- PYRAZOLO[3,4-B]PYRIDIN-1-YL)-3-METHYLBENZAMIDE
DATE LAST MODIFIED
1 May 2019
RELEASE
2 Jan 2019
OBSOLETE
CLASSIFICATION
CHAPERONE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
102.334
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01085
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P07900 | HSP90AA1, HSP90A, HSPC1, HSPCA | ESCHERICHIA COLI BL21(DE3) | HUMAN | HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIA ... | Mutations | |
| P53704 | HSP90AA1, HSP90A, HSPC1, HSPCA | ESCHERICHIA COLI BL21(DE3) | HUMAN | HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIA ... | ||
| P53704 | HSP90AA1, HSP90A, HSPC1, HSPCA | ESCHERICHIA COLI BL21(DE3) | HUMAN | HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIA ... | ||
| P53704 | HSP90AA1, HSP90A, HSPC1, HSPCA | ESCHERICHIA COLI BL21(DE3) | HUMAN | HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIA ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402