5ZZ2

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5ZZ2_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF PDE5 IN COMPLEX WITH INHIBITOR LW1634

DATE LAST MODIFIED

10 Oct 2018

RELEASE

19 Sept 2018

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 31 2 1

RESOLUTION RANGE HIGH

2.6

RESOLUTION RANGE LOW

24.73

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.8B01209

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	O76074	PDE5A, PDE5	ESCHERICHIA COLI BL21	HUMAN	CGMP-BINDING CGMP-SPECIFIC PHOSPHODIESTERASE,CGB-P ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402