6AAK

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6AAK_1

Bioassembly 6AAK_2

Chain 6AAK_A

Chain 6AAK_B

Chain 6AAK_C

Chain 6AAK_D

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GENERAL

TITLE

CRYSTAL STRUCTURE OF JAK3 IN COMPLEX WITH PEFICITINIB

DATE LAST MODIFIED

24 Oct 2018

RELEASE

15 Aug 2018

OBSOLETE

CLASSIFICATION

TRANSFERASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.67

RESOLUTION RANGE LOW

106.4

PUBMED ID

DOI

10.1016/J.BMC.2018.08.005

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P02533	--	--	HUMAN	JANUS KINASE 3,JAK-3
P52333	--	--	HUMAN	JANUS KINASE 3,JAK-3	Mutations
P13647	--	--	HUMAN	JANUS KINASE 3,JAK-3
Q9NWY4	--	--	HUMAN	JANUS KINASE 3,JAK-3

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402