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GENERAL
TITLE
STRUCTURE-BASED DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF IMIDAZO[1,2-B]PYRIDAZINE-BASED P38 MAP KINASE INHIBITORS
DATE LAST MODIFIED
14 Feb 2018
RELEASE
17 Jan 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMC.2017.12.031
PDBe
6ANL
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q61207 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A | BACULOVIRUS EXPRESSION VECTOR PFASTBAC1-HM | HUMAN | MAPK 14,CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRU ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402