6C1R

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6C1R_1

Chain 6C1R_B

Chain 6C1R_L

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN C5A RECEPTOR IN COMPLEX WITH AN ORTHOSTERIC ANTAGONIST PMX53 AND AN ALLOSTERIC ANTAGONIST AVACOPAN

DATE LAST MODIFIED

8 Jan 2020

RELEASE

30 May 2018

OBSOLETE

CLASSIFICATION

MEMBRANE PROTEIN/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.2

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1038/S41594-018-0067-Z

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P21730	CYBC, C5AR1, C5AR, C5R1	SPODOPTERA FRUGIPERDA	HUMAN	CYTOCHROME B-562,C5A ANAPHYLATOXIN CHEMOTACTIC REC ...	Mutations
	P15692	--	--	SYNTHETIC CONSTRUCT	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402