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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN C5A RECEPTOR IN COMPLEX WITH AN ORTHOSTERIC ANTAGONIST PMX53 AND AN ALLOSTERIC ANTAGONIST AVACOPAN
DATE LAST MODIFIED
8 Jan 2020
RELEASE
30 May 2018
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1038/S41594-018-0067-Z

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P0ABE7 CYBC, C5AR1, C5AR, C5R1 SPODOPTERA FRUGIPERDA HUMAN
CYTOCHROME B-562,C5A ANAPHYLATOXIN CHEMOTACTIC REC ...
Mutations
-- -- SYNTHETIC CONSTRUCT --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402