6D1Z

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6D1Z_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF TYROSINE-PROTEIN KINASE RECEPTOR IN COMPLEX WITH 5-(4-FLUOROPHENYL)THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE INHIBITOR

DATE LAST MODIFIED

1 May 2019

RELEASE

2 May 2018

OBSOLETE

CLASSIFICATION

TRANSFERASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

1.87

RESOLUTION RANGE LOW

39.15

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.8B00280

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	O26745	NTRK1, MTC, TRK, TRKA	INSECT CELL EXPRESSION VECTOR PTIE1	HUMAN	NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1,TRK1- ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402