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GENERAL
TITLE
HIGHLY POTENT AND SELECTIVE PLASMIN INHIBITORS BASED ON THE SUNFLOWER TRYPSIN INHIBITOR-1 SCAFFOLD ATTENUATE FIBRINOLYSIS IN PLASMA
DATE LAST MODIFIED
1 May 2019
RELEASE
23 Jan 2019
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.32
RESOLUTION RANGE LOW
74.903
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01139
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P00747 PLG KOMAGATAELLA PASTORIS HUMAN
MICROPLASMIN
Mutations
Q4GWU5 -- -- COMMON SUNFLOWER
SFTI-1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402