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GENERAL
TITLE
HOMO SAPIENS DIHYDROFOLATE REDUCTASE COMPLEXED WITH BETA-NADPH AND 3'- [(2R)-4-(2,4-DIAMINO-6-ETHYLPHENYL)BUT-3-YN-2-YL]-5'-METHOXY-[1,1'- BIPHENYL]-4-CARBOXYLIC ACID
DATE LAST MODIFIED
18 Dec 2019
RELEASE
23 May 2018
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.41
RESOLUTION RANGE LOW
42.364
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2019.02.013

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P00374 DHFR ESCHERICHIA COLI HUMAN -- Mutations
P00374 DHFR ESCHERICHIA COLI HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402