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TITLE
X-RAY STRUCTURE OF BACE1 IN COMPLEX WITH A BICYCLIC ISOXAZOLINE CARBOXAMIDE AS THE P3 LIGAND
EXPRESSION SYSTEM(S)
ESCHERICHIA COLI ,
EXPERIMENT TYPE
X-RAY DIFFRACTION
ORGANISM(S)
HOMO SAPIENS ,
CLASSIFICATION
HYDROLASE
SPACE GROUP:
P 1 21 1
RESOLUTION RANGE HIGH:
2.85
RESOLUTION RANGE LOW:
98.38
DOI:
10.1016/J.BMCL.2018.06.045
EM DATA RESOURCE:
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DATE DEPOSITED:
2018-05-19 00:00:00
DATE RELEASED:
2018-07-25 00:00:00
DATE REVISED:
2020-01-01 00:00:00
BIOLOGICAL ASSEMBLY:
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3D Structure - 6DHC

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6DHC_C
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonyms
6DHC_B P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2
6DHC_C P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2
6DHC_A P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2