6DQ5

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6DQ5_2

Chain 6DQ5_A

Spin

Focus

Transparency

GENERAL

TITLE

LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N43 I.E. 3-((6-(4- ACRYLOYL-1,4-DIAZEPAN-1-YL)-2-(PYRIDIN-2-YL)PYRIMIDIN-4-YL)AMINO) PROPANOIC ACID

DATE LAST MODIFIED

1 Jan 2020

RELEASE

21 Nov 2018

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

1.89

RESOLUTION RANGE LOW

32.97

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.8B01219

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P29375	KDM5A, JARID1A, RBBP2, RBP2	ESCHERICHIA COLI	HUMAN	HISTONE DEMETHYLASE JARID1A,JUMONJI/ARID DOMAIN-CO ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402