6DQC

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6DQC_A

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GENERAL

TITLE

LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N50 I.E. 2-(4-((2- (DIMETHYLAMINO)ETHYL)(ETHYL)CARBAMOYL)-5-(4-METHOXYPHENYL)-1H- PYRAZOL-1-YL)ISONICOTINIC ACID

DATE LAST MODIFIED

1 Jan 2020

RELEASE

12 Jun 2019

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

1.75

RESOLUTION RANGE LOW

35.84

PUBMED ID

DOI

PDBe

6DQC

LIGANDS

173 , 628 , 2879118 , 2694450 , 2730972

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P29375	KDM5A, JARID1A, RBBP2, RBP2	ESCHERICHIA COLI	HUMAN	HISTONE DEMETHYLASE JARID1A,JUMONJI/ARID DOMAIN-CO ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402