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GENERAL
TITLE
SAMHD1 BOUND TO CLOFARABINE-TP IN THE CATALYTIC POCKET AND ALLOSTERIC POCKET
DATE LAST MODIFIED
7 Nov 2018
RELEASE
10 Oct 2018
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1073/PNAS.1805593115
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9Y3Z3 SAMHD1, MOP5 ESCHERICHIA COLI BL21(DE3) HUMAN DNTPASE,DENDRITIC CELL-DERIVED IFNG-INDUCED PROTEIN,DCIP,MONOCYTE PROTEIN 5,MOP-5,SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN1 HUMAN
DNTPASE,DENDRITIC CELL-DERIVED IFNG-INDUCED PROTEI ...
Mutations
Q9Y3Z3 SAMHD1, MOP5 ESCHERICHIA COLI BL21(DE3) HUMAN DNTPASE,DENDRITIC CELL-DERIVED IFNG-INDUCED PROTEIN,DCIP,MONOCYTE PROTEIN 5,MOP-5,SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN1 HUMAN
DNTPASE,DENDRITIC CELL-DERIVED IFNG-INDUCED PROTEI ...
Mutations
Q9Y3Z3 SAMHD1, MOP5 ESCHERICHIA COLI BL21(DE3) HUMAN DNTPASE,DENDRITIC CELL-DERIVED IFNG-INDUCED PROTEIN,DCIP,MONOCYTE PROTEIN 5,MOP-5,SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN1 HUMAN
DNTPASE,DENDRITIC CELL-DERIVED IFNG-INDUCED PROTEI ...
Mutations
Q9Y3Z3 SAMHD1, MOP5 ESCHERICHIA COLI BL21(DE3) HUMAN DNTPASE,DENDRITIC CELL-DERIVED IFNG-INDUCED PROTEIN,DCIP,MONOCYTE PROTEIN 5,MOP-5,SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN1 HUMAN
DNTPASE,DENDRITIC CELL-DERIVED IFNG-INDUCED PROTEI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402